Author

Yunping Deng

University of Tennessee Health Science Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Assay:protein structure· 2 Research Focus:differential expression· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Anton J. ReineriD· 2 shared Ellen SappiD· 2 shared Marian DiFigliaiD· 2 shared Marion Joni· 2 shared Adel BoudiiD· 1 shared Anastasia KhvorovaiD· 1 shared Andrew IwanowicziD· 1 shared Daniel O’ReillyiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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2 shared papersNeuroscience

Anton J. ReinerORCID

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2 papers

Recent·Most cited

Localization of Mutant Huntingtin with HTT Exon1 P90 C-terminal Neoepitope Antibodies in Relation to Regional and Neuronal Vulnerability in Forebrain in Q175 Mice and Human Huntington's Disease

Yunping Deng, Marion Joni, H. Wang, Rachel Cox, Ellen Sapp, Marian DiFiglia, Anton J. Reiner

The paper uses specific antibodies to detect mutant huntingtin fragments in HD mouse models and human brains, showing regional and neuronal differences in accumulation that correlate with vulnerability.

Journal of Huntington s Disease · Dec 23, 2025Peer-reviewedNeuroscience

Mutant Huntingtin exon1 protein detected in mouse brain with neoepitope antibody: effects of CAG repeat expansion, MSH3 silencing, and aggregation

Ellen Sapp, Adel Boudi, Andrew Iwanowicz, Jillian Belgrad, Rachael Miller, Riannon Robertson, Daniel O’Reilly, Ken Yamada, Yunping Deng, Marion Joni, Xueyi Li, Kimberly B. Kegel-Gleason, Anastasia Khvorova, Anton J. Reiner, Neil Aronin M. D, Marian DiFiglia

The paper detects HTT1a protein in Huntington's disease mouse brain using western blot with neo-epitope antibodies and shows that reducing MSH3 lowers HTT1a levels.

bioRxiv · Dec 31, 2024 · PreprintNeuroscience