Author

Yunshu Yang

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Physiology· 1

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Alexey I. NesvizhskiiiD· 1 shared Aren Shah· 1 shared Graham F. BradyiD· 1 shared Kapil K. UpadhyayiD· 1 shared Venkatesha BasruriD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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1 shared paperPhysiology

Alexey I. NesvizhskiiORCID

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1 paper

Recent·Most cited

The inner nuclear membrane protein SUN1 regulates cullin-3 neddylation to maintain insulin signaling

Kapil K. Upadhyay, Yunshu Yang, Aren Shah, Venkatesha Basrur, Alexey I. Nesvizhskii, Graham F. Brady

This study shows that the SUN1 H118Y variant impairs CUL3 neddylation, leading to insulin resistance, and that inhibiting neddylation can restore insulin signaling.

bioRxiv · Apr 20, 2026 · PreprintPhysiology