Extensive membrane lipid remodeling at the host-parasite interface of Toxoplasma gondii
Yuri Nakashima, Sachiko Ishida, Nanaru Mineoka, Sayuri Kuriyama, Miho Yoshida, Tatsunori Masatani, Masahito Asada, Hakimi Hassan, Yoshifumi Nishikawa, AKIKAZU FUJITA
This study identifies the transbilayer distribution of phosphoinositides in Toxoplasma gondii, revealing symmetric localization in the parasitophorous vacuole membrane, contrasting with asymmetric distribution in the parasite plasma membrane.
bioRxiv · Nov 3, 2026 · PreprintCell Biology