Gorilla APOBEC3 restricts SIVcpz and influences lentiviral evolution in great ape cross-species transmissions
Yusuke Nakano, Keisuke Yamamoto, Andrew Soper, Ryuichi Kumata, Hirofumi Aso, Naoko Misawa, Yoriyuki Konno, Izumi Kimura, Shumpei Nagaoka, Guillermo Juarez-Fernandez, Jumpei Ito, Terumasa Ikeda, Yoshio Koyanagi, Reuben S Harris, Kei Sato
This study shows that gorilla APOBEC3G restricts SIVcpz transmission and that a single amino acid change in Vif allows viral evasion, influencing lentiviral evolution in great apes.
bioRxiv · Jul 4, 2018 · PreprintMicrobiology