Yuying Ding

Multifunctional Systems in Synthetic Biology: Single-Stranded DNA Signaling for Precise Control of Gene Activation

This paper introduces a gene activation system using single-stranded DNA signals in compartmentalized droplets, enabling precise control of gene expression through orthogonal promoters and logic-gate operations.

High accuracy methylation identification tools on single molecular level for PacBio HiFi data

The paper introduces hifimeth, a deep learning model that improves 5mC detection accuracy on PacBio HiFi data by using 400 bp context, achieving higher accuracy and F1 score than existing methods.