Author

Xin Lai Bai

State Key Laboratory of Ophthalmology

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

Alberto E. BremauntziD· 1 shared Bo WuiD· 1 shared Chuan‐Le XiaoiD· 1 shared David G. McFaddeniD· 1 shared Florentina VandiveriD· 1 shared James H. McGinnis· 1 shared Jessica A. KilgoreiD· 1 shared Jiwoong KimiD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

Alberto E. BremauntzORCID

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2 papers

Recent·Most cited

Endogenous EWSR1-FLI1 degron alleles enable control of fusion oncoprotein expression in tumor cell lines and xenografts

James H. McGinnis, Alberto E. Bremauntz, Florentina Vandiver, Xin Lai Bai, Jiwoong Kim, Jessica A. Kilgore, Purbita Saha, Ryan A. O’Hara, Yang Xie, Laura A. Banaszynski, Noelle Sevilir Williams, David G. McFadden

This study creates inducible EWSR1-FLI1 degron alleles in tumor cell lines to control fusion oncoprotein expression, showing reversible cell cycle arrest and tumor growth suppression in xenografts.

bioRxiv · Oct 27, 2024 · PreprintCancer Biology

High accuracy methylation identification tools on single molecular level for PacBio HiFi data

Ying Chen, Bo Wu, Yuying Ding, Longjian Niu, Xin Lai Bai, Zhuobin Lin, Chuan‐Le Xiao

The paper introduces hifimeth, a deep learning model that improves 5mC detection accuracy on PacBio HiFi data by using 400 bp context, achieving higher accuracy and F1 score than existing methods.

bioRxiv · Aug 14, 2024 · PreprintBioinformatics