BioinformaticsbioRxivPreprint
High accuracy methylation identification tools on single molecular level for PacBio HiFi data
Ying Chen, Bo Wu, Yuying Ding…·Chuan‐Le Xiao
The paper introduces hifimeth, a deep learning model that improves 5mC detection accuracy on PacBio HiFi data by using 400 bp context, achieving higher accuracy and F1 score than existing methods.