Widespread Epistasis between Cancer Driver Mutations and Allele-Specific Copy Number Variations
Serge Merzliakov, Guanlan Dong, Andrea Castro, Mahad Bihie, Yve Nichols-Evans, Hannah K. Carter, Kuan‐lin Huang
The paper identifies epistatic interactions between cancer driver mutations and allele-specific copy number variations in tumors, showing their impact on patient survival.
bioRxiv · Dec 14, 2025 · PreprintGenomics