Author

Serge Merzliakov

Icahn School of Medicine at Mount Sinai

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 2 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Approach:statistical model· 2 Approach:benchmark study· 1 Assay:bulk RNA-seq· 1 Assay:CRISPR screen· 1 Research Focus:database / resource· 1

Frequent Co-Authors

Kuan‐lin HuangiD· 2 shared Andrea CastroiD· 1 shared C Wang· 1 shared Dongdong Zhang· 1 shared Goutam ChakrabortyiD· 1 shared Guanlan DongiD· 1 shared Hannah K. CarteriD· 1 shared Mahad Bihie· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBioinformatics

Kuan‐lin HuangORCID

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2 papers

Recent·Most cited

An Agentic Platform for Drug Repurposing Unified across Molecular, Phenotypic, and Clinical Scales

C Wang, Mohamed El Moussaoui, Dongdong Zhang, Prathiksha Prabhakaraalva, Serge Merzliakov, Rita Jui-Hsien Lu, Nabila Zaman, Goutam Chakraborty, Kuan‐lin Huang

LinkD is a drug repurposing platform that integrates molecular, phenotypic, and clinical data to prioritize drugs, showing reduced prostate cancer incidence with beta-blockers.

bioRxiv · Jun 7, 2026 · PreprintBioinformatics

Widespread Epistasis between Cancer Driver Mutations and Allele-Specific Copy Number Variations

Serge Merzliakov, Guanlan Dong, Andrea Castro, Mahad Bihie, Yve Nichols-Evans, Hannah K. Carter, Kuan‐lin Huang

The paper identifies epistatic interactions between cancer driver mutations and allele-specific copy number variations in tumors, showing their impact on patient survival.

bioRxiv · Dec 14, 2025 · PreprintGenomics