NeuroscienceNature NeurosciencePeer-reviewed
Lewy pathology in Parkinson's disease consists of a crowded organellar, membranous medley
Sarah H. Shahmoradian, Amanda J. Lewis, Christel Genoud…·Matthias E. Lauer
The paper uses high-resolution imaging and biophysical methods to show that Lewy pathology in Parkinson's disease consists mainly of a crowded membranous medley of vesicles and dysmorphic organelles, with only a small fraction containing proteinaceous filaments.