JAK1 inhibition blocks lethal sterile immune responses:implications for COVID-19 therapy
K. Tuttle, R. Minter, K. Waugh, P. Araya, M. Ludwig, C. Sempeck, K. Smith, Z. Andrysik, M. Burchill, B. Tamburini, D. Orlicky, K. D. Sullivan, J. Espinosa
JAK1 inhibition prevents lethal immune responses and organ failure in a mouse model of Down syndrome and viral infection.
bioRxiv · Apr 7, 2020Immunology