Spatial and temporal organization of RecA in the Escherichia coli DNA-damage response
H. Ghodke, B. Paudel, J. S. Lewis, S. Jergic, K. Gopal, Z. J. Romero, E. A. Wood, R. Woodgate, M. M. Cox, A. M. van Oijen
This study uses a fluorescent probe to track RecA dynamics in live E. coli, showing it is stored during normal metabolism and rapidly mobilizes to form SOS-signaling complexes upon DNA damage.
bioRxiv · Sep 10, 2018Biophysics