Author

E. A. Wood

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Evolutionary Biology· 2 Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:E. coli· 6 Research Focus:cell signaling & trafficking· 4 Approach:experimental assay· 4 Assay:fluorescence / live-cell microscopy· 3 Research Focus:cell type annotation· 2 Approach:microscopy & imaging analysis· 2 Assay:proteomics· 2 Assay:whole-genome sequencing· 2

Frequent Co-Authors

M. M. Cox· 6 shared A. M. van Oijen· 3 shared H. Ghodke· 3 shared A. Robinson· 2 shared S. Jergic· 2 shared S. T. Bruckbauer· 2 shared A. E. McGarth· 1 shared A. Lipzen· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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6 shared papersBiophysics

M. M. Cox

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Spatiotemporal dynamics of single-stranded DNA intermediates in Escherichia coli

M. E. Cherry, K. Dubiel, C. Henry, E. A. Wood, S. A. Revitt-Mills, J. Keck, M. M. Cox, A. M. van Oijen, H. Ghodke, A. Robinson

The paper uses fluorescence microscopy to study the spatiotemporal dynamics of single-stranded DNA in live E. coli cells, revealing patterns associated with DNA repair and replication.

bioRxiv · May 8, 2023 · PreprintBiophysics

Interaction with single-stranded DNA-binding protein modulates Escherichia coli RadD DNA repair activities

M. A. O. Garcia, E. A. Wood, J. L. Keck, M. M. Cox

The paper investigates how RadD interacts with SSB to modulate its ATPase activity and DNA repair functions in E. coli.

bioRxiv · Dec 5, 2022 · PreprintBiochemistry

Experimental evolution of extremophile levels of radiation resistance in Escherichia coli

S. T. Bruckbauer, B. B. Minkoff, T. Shinohara, A. Lipzen, J. Guo, E. A. Wood, M. R. Sussman, C. Pennacchio, M. M. Cox

This study uses experimental evolution to generate E. coli with radiation resistance similar to Deinococcus radiodurans, revealing multiple genomic and proteomic changes involved in IR resistance.

bioRxiv · Oct 18, 2021 · PreprintEvolutionary Biology

Modulation of DNA polymerase IV activity by UmuD and RecA* observed by single-molecule time-lapse microscopy

S. S. Henrikus, A. E. McGarth, S. Jergic, M. L. Ritger, P. T. Pham, E. A. Wood, M. F. Goodman, M. M. Cox, A. M. van Oijen, H. Ghodke, A. Robinson

The paper shows UmuD and RecA modulate DNA polymerase IV binding to DNA substrates, with UmuD inhibiting and RecA promoting association, particularly in DNA-damaged cells.

bioRxiv · Jun 23, 2019 · PreprintMicrobiology

Spatial and temporal organization of RecA in the Escherichia coli DNA-damage response

H. Ghodke, B. Paudel, J. S. Lewis, S. Jergic, K. Gopal, Z. J. Romero, E. A. Wood, R. Woodgate, M. M. Cox, A. M. van Oijen

This study uses a fluorescent probe to track RecA dynamics in live E. coli, showing it is stored during normal metabolism and rapidly mobilizes to form SOS-signaling complexes upon DNA damage.

bioRxiv · Sep 10, 2018Biophysics

A hyperactive variant of the Escherichia coli anaerobic transcription factor FNR enhances ionizing radiation resistance

S. T. Bruckbauer, J. D. Trimarco, E. A. Wood, J. R. Battista, M. M. Cox

This study identifies a hyperactive FNR variant in E. coli that contributes to radiation resistance through altered metabolism, distinct from DNA repair mutations in other resistant populations.

bioRxiv · Jun 11, 2018Evolutionary Biology