BiochemistrybioRxivPreprint
Deep mutational scanning and massively parallel kinetics of plasminogen activator inhibitor-1 functional stability
L. M. Haynes, Z. M. Huttinger, A. Yee…·D. Ginsburg
The paper analyzes PAI-1 variants to identify mutations that increase functional stability and inhibitory activity, and develops a method to measure functional half-lives of hundreds of variants in parallel.
DOI 10.1101/2022.07.19.500671