MicrobiologybioRxiv
Caspase-dependent cleavage of DDX21 suppresses host innate immunity
C. Ding, Y. Sun, W. Wu…·W. Liu
This study identifies DDX21 cleavage by caspase-3/6 during virus infection as a mechanism to suppress IFN-β signaling by disrupting the DDX1-DDX21-DHX36 complex.
DOI 10.1128/mbio.01005-21