Altered immunity of laboratory mice in the natural environment is associated with fungal colonization
F. Yeung, Y.-H. Chen, J.-D. Lin, J. M. Leung, C. McCauley, J. C. Devlin, C. Hansen, A. Cronkite, Z. W. Stephens, C. Drake-Dunn, K. V. Ruggles, J. L. Round, P. Loke, A. L. Graham, K. Cadwell
This study shows that rewilding laboratory mice in an outdoor environment alters their immune system, increasing granulocytes and changing microbiota, but not causing infection from known pathogens.
bioRxiv · Dec 9, 2019Immunology