Author

J.-D. Lin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Approach:experimental assay· 6 Organism:mouse· 5 Research Focus:cell type annotation· 4 Research Focus:differential expression· 4 Assay:bulk RNA-seq· 2 Research Focus:cell-cell communication· 2 Research Focus:host-pathogen & immune response· 2 Assay:scRNA-seq· 2

Frequent Co-Authors

J. C. Devlin· 4 shared K. V. Ruggles· 4 shared P. Loke· 4 shared K. Cadwell· 3 shared A. Cronkite· 2 shared A. L. Graham· 2 shared C. Drake-Dunn· 2 shared C. Hansen· 2 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersImmunology

J. C. Devlin

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Author profile →

6 papers

Recent·Most cited

Serum amyloid A3 deficiency modulates aortic immune composition and attenuates murine atherosclerosis progression

T.-Y. Chou, Y.-Z. Ye, C.-J. Lien, J.-C. Wang, C.-H. Yang, Y.-T. Chen, P.-A. Chao, J.-D. Lin

This study shows that Saa3 deficiency reduces atherosclerosis in mice by altering aortic immune cell composition and function.

bioRxiv · Jul 9, 2024 · PreprintImmunology

Single-cell analysis of CX3CR1+ cells reveal a pathogenic role for BIRC5+ myeloid proliferating cells driven by Staphylococcus aureus leukotoxins

D. G. Loredan, J. C. Devlin, K. A. Lacey, N. Howard, Z. Chen, E. E. Zwack, J.-D. Lin, K. V. Ruggles, K. M. Khanna, V. J. Torres, P. Loke

The paper identifies BIRC5+ myeloid cells as pathogenic during S. aureus infection using scRNA-seq and genetic fate mapping.

bioRxiv · Feb 27, 2023 · PreprintImmunology

The In Vivo Source of Type I and Type III IFNs is Pathogen Dependent

M. J. Sandoval, H.-C. Tseng, H. P. Risman, S. Smirnov, Q. Li, J.-D. Lin, A. Rivera, R. K. Durbin, S. V. Kotenko, J. Durbin

This study identifies pathogen-dependent sources of type I and III IFNs during respiratory virus infection, showing that pDCs produce IFN-{lambda} during IAV infection but not NDV.

bioRxiv · Oct 5, 2021 · PreprintImmunology

Transcriptional Atlas of Ileal-Anal Pouch Immune Cells from Ulcerative Colitis Patients

J. C. Devlin, J. Axelrad, A. Hine, S. Chang, S. Sarkar, J.-D. Lin, K. V. Ruggles, D. Hudesman, K. Cadwell, P. Loke

The paper uses single-cell RNA-sequencing to analyze immune cells in ileal pouches and colons of UC patients, identifying specific cell types and their association with inflammation and treatment response.

bioRxiv · Jul 31, 2020Immunology

Housing laboratory mice deficient for Nod2 and Atg16l1 in a natural environment uncovers genetic and environmental contributions to immune variation.

J.-D. Lin, J. C. Devlin, F. Yeung, C. McCauley, J. M. Leung, Y.-H. Chen, A. Cronkite, C. Hansen, C. Drake-Dunn, K. V. Ruggles, K. Cadwell, A. L. Graham, P. Loke

Exposing mice with genetic mutations to a natural environment reveals environmental effects on immune cell populations and genetic effects on cytokine responses.

bioRxiv · Dec 9, 2019Immunology

Altered immunity of laboratory mice in the natural environment is associated with fungal colonization

F. Yeung, Y.-H. Chen, J.-D. Lin, J. M. Leung, C. McCauley, J. C. Devlin, C. Hansen, A. Cronkite, Z. W. Stephens, C. Drake-Dunn, K. V. Ruggles, J. L. Round, P. Loke, A. L. Graham, K. Cadwell

This study shows that rewilding laboratory mice in an outdoor environment alters their immune system, increasing granulocytes and changing microbiota, but not causing infection from known pathogens.

bioRxiv · Dec 9, 2019Immunology