Z. Xiahou

PLK1 O-GlcNAcylation is essential for dividing mammalian cells and inhibits uterine carcinoma

This study identifies PLK1 O-GlcNAcylation as critical for cell division and shows its role in suppressing uterine carcinoma through biochemical and mouse model experiments.

MYPT1 O-GlcNAcylation Dictates Timely Disjunction of Centrosomes

This study identifies MYPT1 O-GlcNAcylation as a regulator of centrosome disjunction during mitosis, showing that it modulates Plk1 activity and affects cell cycle progression.