Substrate deformation regulates DRM2-mediated DNA methylation in plants
J. Fang, S. M. Leichter, J. Jiang, M. Biswal, J. Lu, Z.-M. Zhang, W. Ren, J. Zhai, Q. Cui, X. Zhong, J. Song
This study identifies DNA deformation as a mechanism regulating DRM2-mediated methylation specificity in plants, showing how substrate deformation influences substrate preference.
bioRxiv · Mar 17, 2020Biochemistry