Beneficial reversal of dominance maintains a resistance polymorphism under fluctuating insecticide selection
Marianthi Karageorgi, Anastasia S. Lyulina, Mark C. Bitter, Egor Lappo, Sharon I. Greenblum, Zach K. Mouza, Caitlynn Tran, Andy V. Huynh, Hayes Oken, PAUL S. SCHMIDT, Dmitri A. Petrov
The paper shows that beneficial reversal of dominance at the Ace locus in Drosophila melanogaster allows resistant alleles to persist under fluctuating insecticide selection.
Nature Ecology & Evolution · Sep 15, 2025Peer-reviewedEvolutionary Biology