Egor Lappo

Pervasive fitness trade-offs revealed by rapid adaptation in large experimental populations of Drosophila melanogaster

This study uses genomic data from Drosophila melanogaster to show how fitness trade-offs manifest under fluctuating selection, identifying genomic regions linked to reproduction and stress tolerance.

Beneficial reversal of dominance maintains a resistance polymorphism under fluctuating insecticide selection

The paper shows that beneficial reversal of dominance at the Ace locus in Drosophila melanogaster allows resistant alleles to persist under fluctuating insecticide selection.

Coalescent theory of the {psi} directionality index

This paper develops theoretical predictions for the directionality index in coalescent models of two populations and analyzes its behavior in Drosophila melanogaster.

Approximations to the expectations and variances of ratios of tree properties under the coalescent

The paper provides Taylor approximations for expected values and variances of ratios of tree properties under the coalescent, showing good agreement with simulations for expectations but less so for variances.