Author

Zain Umer

Lahore University of Management Sciences

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 2 Genetics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:Drosophila· 4 Approach:experimental assay· 4 Research Focus:gene regulatory network inference· 4 Assay:ChIP-seq· 3 Research Focus:differential expression· 3 Research Focus:cell type annotation· 2 Approach:statistical model· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Muhammad Haider Farooq KhaniD· 4 shared Muhammad TariqiD· 4 shared Ammad Shaukat· 3 shared Jawad AkhtariD· 3 shared Najma ShaheeniD· 2 shared Amir FaisaliD· 1 shared Aziz MithaniiD· 1 shared Hina Ahmad· 1 shared

Activity by Year

2021-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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4 shared papersGenomics

Muhammad Haider Farooq KhanORCID

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4 papers

Recent·Most cited

Genome-wide binding of Multiple ankyrin repeats single KH domain reveals its role in maintenance of gene activation by trithorax group proteins in Drosophila

Ammad Shaukat, Muhammad Haider Farooq Khan, Jawad Akhtar, Mahnoor Hussain Bakhtiari, Muhammad Abdul Haseeb, Khalida Mazhar, Zain Umer, Muhammad Tariq

This study identifies Mask as a downstream effector of Trithorax group proteins in Drosophila, showing its role in maintaining gene activation by regulating H3K27ac and H3K27me3 levels.

bioRxiv · Mar 15, 2022 · PreprintGenomics

Interplay between BALL and CBP maintains H3K27 acetylation on active genes in Drosophila

Muhammad Haider Farooq Khan, Ammad Shaukat, Zain Umer, Hina Ahmad, Muhammad Tariq

The paper shows BALL and CBP interact to maintain H3K27ac on active genes in Drosophila, revealing a new pathway for gene activation.

Frontiers in Cell and Developmental Biology · Sep 28, 2021Peer-reviewedGenomics

Polycomb requires Tcp-1η chaperonin for maintaining gene silencing in Drosophila

Najma Shaheen, Jawad Akhtar, Zain Umer, Muhammad Haider Farooq Khan, Murtaza Saleem, Amir Faisal, Muhammad Tariq

This study identifies Tcp-1η as a chaperonin subunit that interacts with Polycomb to maintain gene silencing in Drosophila, supporting its role in PcG targeting and chromatin association.

bioRxiv · Apr 23, 2021 · PreprintGenetics

Kinome-wide RNAi screen uncovers role of Ballchen in maintenance of gene activation by trithorax group in Drosophila

Muhammad Haider Farooq Khan, Jawad Akhtar, Zain Umer, Najma Shaheen, Ammad Shaukat, Muhammad Shahbaz Munir, Aziz Mithani, Saima Anwar, Muhammad Tariq

The paper identifies Ballchen as a trithorax group regulator that counteracts Polycomb group repression by maintaining gene activation through histone modification.

Frontiers in Cell and Developmental Biology · Mar 5, 2021Peer-reviewedMolecular Biology