ImmunologybioRxivPreprint
Microbial induction of MHC-II expression in colon cancer cells overcomes immunotherapy resistance and limits metastasis
Charlie Chung, Elif Ozcelik, J Zhang…·Semir Beyaz
This study shows that a microbiome-dependent mechanism increases MHC-II expression in colon cancer cells, enhancing immunotherapy response and limiting metastasis.