Influenza A Virus H7 nanobody recognizes a conserved immunodominant epitope on hemagglutinin head and confers heterosubtypic protection
Zhao-Shan Chen, Hsiang‐Chi Huang, Xiangkun Wang, Karin Schön, Yane Jia, Michael Lebens, Danica F. Besavilla, Janarthan R. Murti, Yanhong Ji, Aishe A. Sarshad, Guohua Deng, Qiyun Zhu, Davide Angeletti
The paper identifies a nanobody that targets a conserved epitope on influenza A virus H7 hemagglutinin, providing cross-subtype neutralization and protection.
Nature Communications · Jan 9, 2025Peer-reviewedMicrobiology