Author

Zhe Lin

BGI Group (China)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Biology Disciplines

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Genomics· 2

Signature Assays, Organisms & Methods

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Research Focus:variant calling· 2 Organism:human· 1 Approach:machine learning (classical)· 1 Approach:statistical model· 1 Research Focus:variant effect prediction· 1 Assay:whole-exome sequencing· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Chongjun XuiD· 2 shared Andrei Alexeev· 1 shared Ao CheniD· 1 shared Chong TangiD· 1 shared Fang Chen· 1 shared Feng MuiD· 1 shared Han Ren· 1 shared Hanjie Shen· 1 shared

Activity by Year

2019-2019 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersGenomics

Chongjun XuORCID

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2 papers

Recent·Most cited

Advanced Whole Genome Sequencing Using an Entirely PCR-free Massively Parallel Sequencing Workflow

Hanjie Shen, Pengjuan Liu, Zhanqing Li, Fang Chen, Hui Jiang, Shiming Shi, Yang Xi, Qiaoling Li, Xiaojue Wang, Jing Zhao, Xinming Liang, Yinlong Xie, Lin Wang, Wenlan Tian, Tam Berntsen, , Radoje Drmanac

This paper demonstrates that PCR-free whole genome sequencing using the DNBSEQ platform and machine learning variant calling significantly reduces InDel errors and improves variant calling performance.

bioRxiv · Dec 20, 2019 · PreprintGenomics

A new massively parallel nanoball sequencing platform for whole exome research

Yu Xu, Zhe Lin, Chong Tang, Yujing Tang, Yue Cai, Hongbin Zhong, Xuebin Wang, Wenwei Zhang, Chongjun Xu, Jingjing Wang, jian Zi Wang, Huanming Yang, Linfeng Yang, Qiang Gao

This study evaluates the BGISEQ-500 platform for whole exome sequencing, finding it comparable to Hiseq4000 in SNP detection and slightly better in indel detection.

BMC Bioinformatics · Mar 25, 2019Peer-reviewedGenomics