Protein Engineering for Thermostability through Deep Evolution
Huanyu Chu, Zhenyang Tian, Lingling Hu, Hejian Zhang, Hong Yi Chang, Jie Bai, Dingyu Liu, Jian Cheng, Huifeng Jiang
This study develops DeepEvo, a deep learning approach for engineering thermostable proteins, achieving 8 highly thermostable variants from 30 generated sequences.
bioRxiv · May 4, 2023 · PreprintBioinformatics