Huifeng Jiang

PANDA generates high-quality all-atom protein structures by denoising atomic occupancy patterns, achieving high self-consistency and scaffolding success on functional design tasks.

This study identifies FoTO1 as an epoxide isomerase that facilitates the productive rearrangement of taxadiene-4(5)-epoxide in paclitaxel biosynthesis.

This paper develops inducible bacterial cellulose production in Enterobacter sp. FY-07 using genetic engineering, achieving over 80% recovery of BC production and demonstrating altered BC properties.

The paper designs artificial cytochrome P450 enzymes by applying a 'three-point fixation' model derived from structural and evolutionary analysis, resulting in enzymes with enhanced catalytic activity.

This study develops DeepEvo, a deep learning approach for engineering thermostable proteins, achieving 8 highly thermostable variants from 30 generated sequences.

This paper designs and tests a minimal artificial glycolytic pathway that efficiently converts various monosaccharides to acetyl-CoA with high yield.