Jian Cheng

The paper develops population-specific white matter charts for Chinese and Western populations, showing differences in maturation timing and improved prediction accuracy when using population-matched models.

This study identifies FoTO1 as an epoxide isomerase that facilitates the productive rearrangement of taxadiene-4(5)-epoxide in paclitaxel biosynthesis.

This study examines how structural and functional brain connectivity develop and relates to cognitive functions and gene expression in humans.

The paper designs artificial cytochrome P450 enzymes by applying a 'three-point fixation' model derived from structural and evolutionary analysis, resulting in enzymes with enhanced catalytic activity.

This study develops DeepEvo, a deep learning approach for engineering thermostable proteins, achieving 8 highly thermostable variants from 30 generated sequences.