Author

Zhenyu Xi

Texas A&M University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

David H. RusselliD· 2 shared Adam Hillaire· 1 shared Amy Spelbring· 1 shared Arthur D. LaganowskyiD· 1 shared Carter LantziD· 1 shared D.P. BarondeauiD· 1 shared David E. ClemmeriD· 1 shared Elena Scott· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersBiochemistry

David H. RussellORCID

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2 papers

Recent·Most cited

Site Specific Hydration Contributes to the Thermal Stability of Proteins and Protein-Complexes

Robert L. Rider, Zhenyu Xi, Adam Hillaire, Joanna Powell, Amy Spelbring, Kacie A. Evans, Carter Lantz, Elena Scott, D.P. Barondeau, Shannon Raab, David E. Clemmer, Arthur D. Laganowsky, David H. Russell

This study investigates how site-specific hydration affects the thermal stability of proteins and protein complexes using D2O and experimental methods, revealing that stabilization depends on both hydration extent and water interaction sites.

bioRxiv · Oct 28, 2026 · PreprintBiochemistry

Unveiling the Hidden: Dissecting Liraglutide Oligomerization Dual Pathways via Direct Mass Technology, Electron-Capture Dissociation, and Molecular Dynamics

Syuan-Ting Alex Kuo, Zhenyu Xi, Xiao Cong, Xin Yan, David H. Russell

This study uses mass spectrometry techniques to reveal dual oligomerization pathways of liraglutide, highlighting structural changes and interactions involved in aggregation.

bioRxiv · Feb 27, 2025 · PreprintBiophysics