BiochemistrybioRxivPreprint
Site Specific Hydration Contributes to the Thermal Stability of Proteins and Protein-Complexes
Robert L. Rider, Zhenyu Xi, Adam Hillaire…·David H. Russell
This study investigates how site-specific hydration affects the thermal stability of proteins and protein complexes using D2O and experimental methods, revealing that stabilization depends on both hydration extent and water interaction sites.
DOI 10.64898/2026.10.26.761984