Semi-rational Engineering of Terminal Deoxynucleotidyl Transferase for High-efficiency Enzymatic de Novo DNA Synthesis
Chengjie Zhang, Zhicong He, Zhengquan Gao, Chunxiao Meng, Peng Wei, Lei Du, Shengying Li
This paper engineers terminal deoxynucleotidyl transferase (TdT) to improve enzymatic DNA synthesis efficiency and scalability.
Synthetic and Systems Biotechnology · Mar 25, 2026Peer-reviewedSynthetic Biology