Author

Zhiyu Yang

University of Helsinki

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Genetic & Genomic Medicine· 2 Cell Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:differential expression· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Assay:electronic health records· 1

Frequent Co-Authors

Andrea GannaiD· 2 shared Bradley S. JermyiD· 1 shared Changhan CheniD· 1 shared Chenggang CheniD· 1 shared Jiayue Gao· 1 shared Juan Liu· 1 shared Kira E. DetroisiD· 1 shared Kristi KrebsiD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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2 shared papersGenetic & Genomic Medicine

Andrea GannaORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Glucocorticoid Programming of Erythrocyte Hypoxic Memory Enables Rapid High-Altitude Acclimatization

丑天胜, Yu Zhang, X Yu, Jiayue Gao, Changhan Chen, W.T. Liu, Juan Liu, Zhiyu Yang, Rodney Eugene Kellems, Lingling Zhu, Xia Yang

This study identifies glucocorticoids as mediators of hypoxic memory in erythrocytes that enhance oxygen delivery and reduce AMS severity through metabolic reprogramming.

bioRxiv · May 30, 2026 · PreprintCell Biology

What and where manifolds emerge and align with perception in deep neural network models of sound localization

Chenggang Chen, Zhiyu Yang, Xiaoqin Wang

This study examines how deep neural networks model 'what' and 'where' in sound localization, finding that 'what' manifolds are geometrically organized and influence 'where' map formation, with implications for understanding brain function.

bioRxiv · Feb 12, 2026 · PreprintNeuroscience

Machine learning augmented genome-wide meta-analysis of prescription opioid use in 860,000 individuals

Lisa Eick, Laura Birgit Luitva, Kristi Krebs, Sakari Jukarainen, Sami Kulju, Maiju K. Marttinen, Manuel A. Rivas, Andrea Ganna, Lili A. Milani, Zhiyu Yang, Tuomo Kiiskinen

The paper uses genome-wide meta-analysis and machine learning to study prescription opioid use in 860,000 individuals, identifying genetic loci and distinguishing between pain-related and dose-intensity traits.

medRxiv · Dec 15, 2025 · PreprintGenetic & Genomic Medicine

Transferability and accuracy of electronic health record-based predictors compared to polygenic scores

Kira E. Detrois, Tuomo Hartonen, Maris Teder‐Laving, Bradley S. Jermy, Kristi Läll, Zhiyu Yang, Reedik Mägi, Samuli Ripatti, Andrea Ganna

This study compares EHR-based phenotype risk scores (PheRS) and polygenic scores (PGS) for predicting 13 diseases, finding they capture independent information and improve prediction when combined.

medRxiv · Oct 8, 2024 · PreprintGenetic & Genomic Medicine