Au18(L-NIBC)14 targets ASC oligomerization for autoimmune disease treatment
Kai Yang, Xinyue Zhao, Zhupeng Xiao, Cheng Zeng, Lei Shen, Taolei Sun
This study identifies Au18(L-NIBC)14 as a gold nanocluster that targets ASC oligomerization, reducing inflammasome activation and improving symptoms in autoimmune disease models.
bioRxiv · Mar 25, 2025 · PreprintPharmacology & Toxicology