ALS Motor Neurons Exhibit Hallmark Metabolic Defects That Are Rescued by Nicotinamide and SIRT3 Activation
Jin‐Hui Hor, Munirah Mohamad Santosa, Valerie Jing Wen Lim, Beatrice Xuan Ho, Amy Taylor, Zi Jian Khong, John Ravits, Yong Fan, Yih‐Cherng Liou, Boon-Seng Soh, Shi‐Yan Ng
This study identifies metabolic defects in ALS motor neurons and shows that nicotinamide and SIRT3 activation can rescue these defects.
Cell Death and Differentiation · Nov 12, 2020Peer-reviewedNeuroscience