Author

Ziliang Zhu

University of North Carolina at Chapel Hill

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 6 Genetic & Genomic Medicine· 3 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 10 Approach:statistical model· 10 Research Focus:GWAS / association mapping· 8 Assay:imaging· 5 Assay:bulk RNA-seq· 3 Research Focus:gene regulatory network inference· 2 Research Focus:differential expression· 1 Research Focus:fine-mapping· 1

Frequent Co-Authors

Hongtu Zhu BiD· 10 shared Tengfei LiiD· 10 shared Bingxin ZhaoiD· 9 shared Yue ShaniD· 9 shared Yun LiiD· 8 shared Tianyou LuoiD· 7 shared Xifeng WangiD· 6 shared Yue YangiD· 6 shared

Activity by Year

2018-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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10 shared papersGenetics

Hongtu Zhu BORCID

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10 papers

Recent·Most cited

Genetic influences on the shape of brain ventricular and subcortical structures

Bingxin Zhao, Tengfei Li, Xiaochen Yang, Juan Shu, Xifeng Wang, Tianyou Luo, Yue Yang, Zhenyi Wu, Zirui Fan, Zhiwen Jiang, Jie Chen, Yue Shan, Jiarui Tang, Di Xiong, Ziliang Zhu, , Hongtu Zhu B

The paper identifies 60 genetic loci associated with brain ventricular and subcortical shape features using shape measures from over 45,000 UK Biobank and ABCD study subjects.

medRxiv · Sep 26, 2022 · PreprintGenetic & Genomic Medicine

Jointly analyzing the association of human milk nutrients with cognition and temperament traits during the first 6 months of life

Tengfei Li, Tinu Mary Samuel, Ziliang Zhu, Brittany Howell, Seoyoon Cho, Kristine Baluyot, Heather C. Hazlett, Jed T. Elison, Di Wu, Jonas Hauser, Norbert Sprenger, Hongtu Zhu B, Weili Lin

The paper examines how various human milk nutrients are associated with cognitive and temperament traits in infants up to 18 months old, finding persistent effects of certain nutrients on development.

bioRxiv · Apr 24, 2022 · PreprintDevelopmental Biology

Common variants contribute to intrinsic human brain functional networks

Bingxin Zhao, Tengfei Li, Stephen M. Smith, Di Xiong, Xifeng Wang, Yue Yang, Tianyou Luo, Ziliang Zhu, Yue Shan, Nana Matoba, Quan Sun, Yuchen Yang, Mads E. Hauberg, Jaroslav M. Bendl, John F. Fullard, , Hongtu Zhu B

This study identifies common genetic variants influencing intrinsic brain networks using rsfMRI data from 44,190 individuals, finding associations with cognitive and clinical traits.

Nature Genetics · Apr 1, 2022Peer-reviewedGenetics

Heart-brain connections: phenotypic and genetic insights from 40,000 cardiac and brain magnetic resonance images

Bingxin Zhao, Tengfei Li, Zirui Fan, Yue Yang, Xifeng Wang, Tianyou Luo, Jiarui Tang, Di Xiong, Zhenyi Wu, Jie Chen, Yue Shan, Chal E. Tomlinson, Ziliang Zhu, Yun Li, Jason L. Stein, Hongtu Zhu B

The paper investigates phenotypic and genetic links between heart and brain using MRI data from 40,000 UK Biobank subjects, finding strong correlations and shared genetic influences.

medRxiv · Nov 1, 2021 · PreprintGenetic & Genomic Medicine

Genetic influences on the intrinsic and extrinsic functional organizations of the cerebral cortex

Bingxin Zhao, Tengfei Li, Stephen M. Smith, Zirui Fan, Xiaochen Yang, Yilin Yang, Juan Shu, Di Xiong, Xifeng Wang, Yue Yang, Tianyou Luo, Ziliang Zhu, Yue Shan, Yujue Li, Zhenyi Wu, , Hongtu Zhu B

This study identifies genetic loci associated with functional brain networks and areas using large-scale fMRI data, linking them to cognitive traits and brain disorders.

medRxiv · Jul 27, 2021 · PreprintGenetic & Genomic Medicine

Common genetic variation influencing human white matter microstructure

Bingxin Zhao, Tengfei Li, Yue Yang, Xifeng Wang, Tianyou Luo, Yue Shan, Ziliang Zhu, Di Xiong, Mads E. Hauberg, Jaroslav M. Bendl, John F. Fullard, Panos Roussos, Yun Li, Jason L. Stein, Hongtu Zhu B

This study identifies common genetic variants influencing white matter microstructure using dMRI data from 42,919 individuals, revealing genetic links to neuropsychiatric disorders and other traits.

Science · Jun 17, 2021Peer-reviewedGenetics

Transcriptome-wide association analysis of 211 neuroimaging traits identifies new genes for brain structures and yields insights into the gene-level pleiotropy with other complex traits

Bingxin Zhao, Yue Shan, Yue Yang, Tengfei Li, Tianyou Luo, Ziliang Zhu, Yun Li, Hongtu Zhu B

This study performs transcriptome-wide association analysis on 211 neuroimaging traits, identifies 204 genes, and shows TWAS-derived polygenic risk scores explain up to 6.97% of phenotypic variance.

bioRxiv · Nov 15, 2019 · PreprintGenetics

GWAS of 19,629 individuals identifies novel genetic variants for regional brain volumes and refines their genetic co-architecture with cognitive and mental health traits

Bingxin Zhao, Tianyou Luo, Tengfei Li, Yun Li, Jingwen Zhang, Yue Shan, Xifeng Wang, Liuqing Yang, Fan Zhou, Ziliang Zhu, Alzheimer’s Disease Neuroimaging Initiative, Pediatric Imaging, Neurocognition and Genetics, Hongtu Zhu B

This study identifies 287 novel genetic variants associated with brain volumes using GWAS in 19,629 UK Biobank participants and finds genetic correlations with cognitive and mental health traits.

Nature Genetics · Nov 1, 2019Peer-reviewedGenetics

Large-scale GWAS reveals genetic architecture of brain white matter microstructure and genetic overlap with cognitive and mental health traits (n=17,706)

Bingxin Zhao, Jingwen Zhang, Joseph G. Ibrahim, Rebecca Santelli, Yun Li, Tengfei Li, Yue Shan, Ziliang Zhu, Fan Zhou, Huiling Liao, Thomas E. Nichols, Hongtu Zhu B

bioRxiv · Mar 24, 2019 · PreprintGenetics

Heritability of regional brain volumes in large-scale neuroimaging and genetic studies

Bingxin Zhao, Joseph G. Ibrahim, Yun Li, Tengfei Li, Yue Wang, Yue Shan, Ziliang Zhu, Fan Zhou, Jingwen Zhang, Chao Huang, Huiling Liao, Liuqing Yang, Paul M. Thompson, Hongtu Zhu B, Pediatric Imaging, Neurocognition and Genetics (PING), , John Hsiao

The paper examines the heritability of regional brain volumes using genetic and neuroimaging data from multiple cohorts, finding high heritability and consistent patterns across populations.

Cerebral Cortex · Jul 2, 2018Peer-reviewedGenetics