DNA-triggered AIM2 condensation orchestrates immune activation and regulation
Quanjin Li, Xiaohan Geng, Huiwen Yan, Zhaolong Li, Miao Shi, Ziqi Zhu, Tongxin Niu, Chunqiu Zhao, Kaile Shu, Yina Gao, Han Feng, Songqing Liu, Qiuyao Jiang, Pengcheng Bu, Dong Li, Pu Gao
This study shows AIM2 forms DNA-induced condensates that drive immune activation and regulation through inflammasome and PANoptosome assembly.
Protein & Cell · Mar 22, 2026Peer-reviewedImmunology