Tongxin Niu

cryoAgent: An agentic workflow for robust and adaptive end-to-end cryo-EM image processing

cryoAgent improves cryo-EM image processing by enabling autonomous, adaptive workflows that enhance reconstruction quality and identify new structural states.

DNA-triggered AIM2 condensation orchestrates immune activation and regulation

This study shows AIM2 forms DNA-induced condensates that drive immune activation and regulation through inflammasome and PANoptosome assembly.

Structural and Mechanistic Insights into Symmetry Conversion in Plant GORK K+ Channel Regulation

The paper solves the cryo-EM structure of Arabidopsis GORK, revealing symmetry reduction driven by ANK dimerization, which regulates K+ channel activity in guard cells.

DeepETPicker: Fast and accurate 3D particle picking for cryo-electron tomography using weakly supervised deep learning

DeepETPicker improves 3D particle picking in cryo-electron tomography with weakly supervised deep learning, achieving higher accuracy and speed than existing methods.