Crystallographic fragment screening of CDK2-cyclin A: FragLites map sites of protein-protein interaction
Ian Hope, Mathew P. Martin, Ziwei Jiang, Michael J. Waring, Martin E. M. Noble, J. A. Endicott, Natalie J. Tatum
The paper uses X-ray crystallographic screening with FragLite to map protein-protein interaction sites on CDK2-cyclin A, identifying known and potential new interaction sites.
Structure · Aug 15, 2025Peer-reviewedBiophysics