Author

ziyan zhang

Guangzhou National Laboratory;

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Biology Disciplines

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Bioinformatics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:contrastive learning· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

Han Yu· 1 shared Jinmeng LiuiD· 1 shared junxiang dingiD· 1 shared liu yang· 1 shared Lu ZhangiD· 1 shared Mingzhong Zhao· 1 shared Rongbo Shen· 1 shared Wenjing WangiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperMicrobiology

Han Yu

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2 papers

Recent·Most cited

GeneEmbedLLM: Harnessing Large Language Models for Gene Functional Embedding and Association Prediction

ziyan zhang, liu yang, zhien he, junxiang ding, Yixue Li, Rongbo Shen

This paper introduces GeneEmbedLLM, a framework using large language models to generate gene embeddings from multi-source textual annotations, achieving competitive performance in various downstream tasks.

bioRxiv · Nov 9, 2026 · PreprintBioinformatics

The Two-Component System CrdRS Mediates Sub-inhibitory Antibiotic-Induced Biofilm Formation in Helicobacter pylori via Bidirectional Regulation of Transporters PlpA and GlnP

Wenxin Zhang, Lu Zhang, Yanlin Sun, Mingzhong Zhao, 徐书景, Han Yu, Wenjing Wang, Jinmeng Liu, Wenyue Ma, Xiaoyu Wang, Ziyan Zhang, Yundong Sun

This study identifies the CrdRS two-component system as a key regulator of antibiotic-induced biofilm formation in H. pylori through bidirectional control of transporters PlpA and GlnP.

Antimicrobial Agents and Chemotherapy · Oct 5, 2026Peer-reviewedMicrobiology