The Two-Component System CrdRS Mediates Sub-inhibitory Antibiotic-Induced Biofilm Formation in Helicobacter pylori via Bidirectional Regulation of Transporters PlpA and GlnP
Wenxin Zhang, Lu Zhang, Yanlin Sun, Mingzhong Zhao, 徐书景, Han Yu, Wenjing Wang, Jinmeng Liu, Wenyue Ma, Xiaoyu Wang, Ziyan Zhang, Yundong Sun
This study identifies the CrdRS two-component system as a key regulator of antibiotic-induced biofilm formation in H. pylori through bidirectional control of transporters PlpA and GlnP.
Antimicrobial Agents and Chemotherapy · Oct 5, 2026Peer-reviewedMicrobiology