Increased cerebrospinal fluid and plasma apoE glycosylation is associated with reduced levels of Alzheimer's disease biomarkers
Dobrin Nedelkov, Zoe E. Tsokolas, Matheus Scarpatto Rodrigues, Isabel J. Sible, S. Duke Han, Bilal E. Kerman, Michael Renteln, Wendy Jean Mack, Tharick Ali Pascoal, Hussein N. Yassine, the Alzheimer’s Disease Neuroimaging Initiative
The paper examines apoE glycosylation in CSF and plasma samples from ADNI, finding reduced glycosylation in MCI and progressors, and associations with AD biomarkers like t-tau, p-tau181, and Aβ1-42.
Alzheimer s Research & Therapy · Jul 10, 2025Peer-reviewedNeuroscience