Bilal E. Kerman

This study shows cPLA2 overactivation is linked to synaptic loss and cognitive decline in Alzheimer's disease through increased eicosanoids and altered synaptic marker interactions.

This study identifies a potent cPLA2 inhibitor, BRI-50460, that modulates neuroinflammation and lipid homeostasis in Alzheimer's disease models.

The paper examines apoE glycosylation in CSF and plasma samples from ADNI, finding reduced glycosylation in MCI and progressors, and associations with AD biomarkers like t-tau, p-tau181, and Aβ1-42.

This study identifies microglia as key contributors to senescence in Alzheimer's disease, linking cholesterol dysregulation to senescence pathologies through transcriptomic analysis of multiple datasets.

DeepMQ quantifies myelin sheaths in fluorescence images of mouse stem cell-derived cells with 93.38% accuracy using a feature extraction and deep learning classification approach.