Michael Renteln

Evidence for cPLA2 activation in Alzheimer's Disease Synaptic Pathology

This study shows cPLA2 overactivation is linked to synaptic loss and cognitive decline in Alzheimer's disease through increased eicosanoids and altered synaptic marker interactions.

Increased cerebrospinal fluid and plasma apoE glycosylation is associated with reduced levels of Alzheimer's disease biomarkers

The paper examines apoE glycosylation in CSF and plasma samples from ADNI, finding reduced glycosylation in MCI and progressors, and associations with AD biomarkers like t-tau, p-tau181, and Aβ1-42.

Exercise alters cortico-basal ganglia network functional connectivity: A mesoscopic level analysis informed by anatomic parcellation defined in the mouse brain connectome

This study examines how exercise affects functional connectivity in the cortico-basal ganglia network in mice, revealing changes in connectivity patterns and metabolic activity in specific brain regions.