Single-cell transcriptomic profiling of human pancreatic islets reveals genes responsive to glucose exposure over 24 hours
Caleb M. Grenko, Henry J. Taylor, Lori L. Bonnycastle, Dongxiang Xue, Brian N. Lee, Zoe Weiss, Tingfen Yan, Amy J. Swift, Erin C. Mansell, Angela Lee, Catherine C. Robertson, Narisu Narisu, Michael R. Erdos, Shuibing Chen, Francis S. Collins, D. Leland Taylor
This study uses single-cell RNA sequencing to analyze gene expression changes in human pancreatic islets under different glucose conditions over 24 hours, identifying genes and modules associated with time, glucose exposure, and their interaction.
Diabetologia · Jul 5, 2024Peer-reviewedGenetics