Disruption of glutamine carrier Slc38a1 causes cognitive impairment, anxiety and depressive-like behavior
Zubeide Sleeman, Gezime Seferi, Prabhat Khanal, Knut Tomas Dalen, Cecilie Morland, Farrukh Abbas Chaudhry
This study shows that disrupting Slc38a1 in mice leads to cognitive impairments, anxiety, and depressive-like behaviors, linking GABAergic dysfunction to these conditions.
bioRxiv · May 22, 2026 · PreprintAnimal Behavior & Cognition