Author

Jacek Mokrosiński

University of CambridgeORCID 0000-0001-5008-0457Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 1 Zoology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Aaron NovikoffiD· 1 shared Alexander MörseburgiD· 1 shared Alice WilliamsoniD· 1 shared Audrey MelviniD· 1 shared BARENT N. DUBOIS· 1 shared Brian FinaniD· 1 shared Brian LamiD· 1 shared Chen ZhangiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperZoology

Aaron NovikoffORCID

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2 papers

Recent·Most cited

ZoologyMolecular MetabolismPeer-reviewedFeb 5, 2026

Ectopic, hepatic GLP-1R agonism enhances the weight loss efficacy of GLP-1 analogues.

Jonathan D. Douros, Megan E. Capozzi, Aaron Novikoff…·Patrick J. Knerr

The paper shows that combining GLP-1R agonists with ectopic hepatic GLP-1R expression enhances weight loss in mice by increasing energy expenditure and reducing food intake.

1 citation

mouseexperimental assay

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Genetic & Genomic MedicineNature MedicinePeer-reviewedMay 27, 2021

Prevalence and expressivity of loss of function mutations in the Melanocortin 4 Receptor (MC4R) in a UK birth cohort

Kaitlin Hazel Wade, Brian Lam, Audrey Melvin…·Stephen O’Rahilly

The paper identifies the prevalence and phenotypic impact of loss of function mutations in the MC4R gene in a UK birth cohort, finding a 0.30% carrier rate with significant effects on body weight and BMI.

134 citationstop 1%

humanstatistical model

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