A family of E3 ligases extend K11 polyubiquitin on sites of MARUbylation
Rachel E. Lacoursiere, Kapil Upadhyaya, Jasleen Kaur Sidhu, Daniel S. Bejan, Ivan Rodriguez Siordia, Michael S. Cohen, Jonathan N. Pruneda
The paper identifies RNF114 as an E3 ligase that extends K11 polyubiquitin on MARUbylated sites, revealing a novel mechanism of Ub-ADPr recognition and polyubiquitylation.
bioRxiv · May 11, 2025 · PreprintBiochemistry