BioengineeringNature Structural & Molecular BiologyPeer-reviewed
Structure-guided discovery and engineering of miniature CRISPR-Cas12m for epigenome editing
Tao Yu, Meng Ji, Donglin Yu…·Kailong Li
This paper identifies and engineers a miniature CRISPR-Cas12m variant for epigenome editing, demonstrating its effectiveness in human cells and a mouse model of HBV infection.