Itai Rusinek

This paper introduces ppmSeq, a sequencing technology that improves accuracy and efficiency in detecting SNVs by sequencing both DNA strands, showing superior performance in clinical applications like ctDNA detection.

This study applies low-cost whole genome sequencing to detect circulating tumor DNA at high sensitivity in plasma samples, achieving error rates as low as 10^-7 and enabling cancer monitoring without matched tumor sequencing.

The paper describes a method to rapidly discover tumoricidal DNA oligonucleotides using an Illumina sequencing chip by mapping apoptotic responses to specific oligo clusters.

This paper describes an in-vitro evolution platform for discovering DNA oligonucleotides with tumoricidal activity and selectivity, showing efficacy against chemotherapy-resistant tumors.