Author

Ariel Jaimovich

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 4

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:experimental assay· 3 Research Focus:variant calling· 2 Assay:whole-genome sequencing· 2 Assay:ChIP-seq· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Assay:Hi-C· 1

Frequent Co-Authors

Doron LipsoniD· 3 shared Gat Krieger· 3 shared Aaron M. HorningiD· 2 shared Adam J. WidmaniD· 2 shared Alexandre Pellan ChengiD· 2 shared Annika K K WeimeriD· 2 shared Ashish SaxenaiD· 2 shared Dan Avi LandauiD· 2 shared

Activity by Year

2022-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersGenomics

Doron LipsonORCID

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4 papers

Recent·Most cited

Paired plus-minus sequencing is an ultra-high throughput and accurate method for dual strand sequencing of DNA molecules

Alexandre Pellan Cheng, Itai Rusinek, Aaron Sossin, Adam J. Widman, Eti Meiri, Gat Krieger, Ori Hirschberg, Doron Shem Tov, Shlomit Gilad, Ariel Jaimovich, Omer Barad, Sammantha Avaylon, Srinivas Rajagopalan, Abigail G. Thress, Catherine J. Potenski, , Dan Avi Landau

This paper introduces ppmSeq, a sequencing technology that improves accuracy and efficiency in detecting SNVs by sequencing both DNA strands, showing superior performance in clinical applications like ctDNA detection.

bioRxiv · Aug 11, 2025 · PreprintGenomics

Global loss of promoter-enhancer connectivity and rebalancing of gene expression during early colorectal cancer carcinogenesis

Yizhou Zhu, Hayan Lee, Shannon M. White, Annika K K Weimer, Emma Monte, Aaron M. Horning, Stephanie A. Nevins, Edward D. Esplin, Kristina Paul, Gat Krieger, Zohar Shipony, Roxanne Chiu, Rozelle Laquindanum, Thomas V. Karathanos, Melissa W. Y. Chua, , Michael P. Snyder

This study shows that early colorectal cancer loses promoter-enhancer connectivity, leading to gene expression changes and a two-phase model of transcriptional regulation.

Nature Cancer · Oct 30, 2024Peer-reviewedGenomics

Whole genome error-corrected sequencing for sensitive circulating tumor DNA cancer monitoring

Alexandre Pellan Cheng, Adam J. Widman, Anushri Arora, Itai Rusinek, William F. Hooper, Rebecca L. Murray, Daniel Halmos, Theophile Langanay, Giorgio Inghirami, Søren Germer, Melissa Marton, Dina Manaa, Adrienne Helland, Rob Furatero, Jaime McClintock, , Dan Avi Landau

This study applies low-cost whole genome sequencing to detect circulating tumor DNA at high sensitivity in plasma samples, achieving error rates as low as 10^-7 and enabling cancer monitoring without matched tumor sequencing.

bioRxiv · Nov 17, 2022 · PreprintGenomics

Ultra high-throughput whole-genome methylation sequencing reveals trajectories in precancerous polyps to early colorectal adenocarcinoma

Hayan Lee, Gat Krieger, Tyson A. Clark, Aziz Khan, Casey Ryan Hanson, Yizhou Zhu, Nasim Bararpour, Aaron M. Horning, Edward D. Esplin, Stephanie A. Nevins, Annika K K Weimer, Eti Meiri, Shlomit Gilad, Sima Benjamin, Danit Lebanony, , Michael P. Snyder

The paper uses ultra high-throughput methylation sequencing to study DNA methylation changes during colorectal cancer progression from normal tissue to adenocarcinoma.

bioRxiv · May 30, 2022 · PreprintGenomics